标题：Antibacterial hydrogel coating by electrophoretic co-deposition of chitosan/alkynyl chitosan作者：Ding, Fuyuan; Nie, Zhen; Deng, Hongbing; Xiao, Ling; Du, Yumin; Shi,Xiaowen

来源出版物：CARBOHYDRATE POLYMERS 卷：98 期：2 页：1547-1552 DOI：10.1016/j.carbpol.2013.07.042出版年：NOV 6 2013

摘要： Despite much effort has been paid to develop aseptic implant devices, the infection associated with medical implant still remains a significant problem. Here, we report a potential coating material derived from a natural biopolymer chitosan. Firstly, chitosan functionalized with alkynyl moiety (ACS) was prepared by reaction between chitosan and 3-bromopropyne. The structure of the alkynyl chitosan was characterized by FT-IR, H-1 NMR, XRD, TGA and element analysis. The minimum inhibitory concentration (MIC) of ACS with a degree of substitution (DS) of 0.40 was 0.03% against Escherichia coil (E. coil) and Staphylococcus aureus (S. aureus). Subsequently, the alkynyl chitosan was co-deposited with chitosan on stainless steel wire to fabricate a composite hydrogel. The composite hydrogel exhibited better antibacterial activities than pure chitosan hydrogel.

入藏号：

文献类型：Article

语种：English

作者关键词：Alkynyl chitosan, Antibacterial activity, Electrophoretic co-deposition, Chitosan, Composite hydrogel

扩展关键词：DERIVATIVES; CHITIN; FILMS; ELECTRODEPOSITION; TITANIUM; BEHAVIOR; SALT

通讯作者地址：Shi,Xiaowen ;Wuhan Univ, Sch Resource & Environm Sci, Wuhan 430079, Peoples R China.

电子邮件地址：shixwwhu@163.com

地址：

[Shi, Xiaowen] Wuhan Univ, Sch Resource & Environm Sci, Wuhan 430079, Peoples R China. Wuhan Univ, Hubei Biomass Resource Chem & Environm Biotechnol, Wuhan 430079, Peoples R China.

研究方向：Chemistry; Polymer Science

ISSN：0144-8617